Yazar "Kayağil, İsmail" için listeleme
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The effects of some imidazopyrazine derivatives on telomerase inhibition, mtDNA damage and mtDNA copy number
Mutlu, Ayşe Gül; Bilginer, Abdulkerim; Kayağil, İsmail; Yıldız, Hülya; Bayhan, Ülkü; Yılmaz, İnanç; Demirayak, Şeref (University of Istanbul, 2017)Imidazopyrazine derivatives have been studied for their curative effects on some diseases like cancer and neurological problems; also, some of these molecules have been patented. Primary human cells exhibit limited replicative ... -
Synthesis, structure elucidation and determination of acid dissociation constant, tautomerism of pyrido [1,2-a] benzimidazole-2,4-dione
Kayağil, İsmail; Tay, Naime Funda; Konak, Hüseyin Yaşar; İspir, Cihan; Demirayak, Şeref (University of Istanbul, 2016)The first starting material, 1H-2-acetylbenzimidazole, 4, was synthesized by o-phenylenediamine, 1, and lactic acid solution, 2, in hydrochloric acid medium on the first step than, oxidation reaction was performed by CrO3 ...